学术报告

发布时间:2017年05月19日 作者:唐颖   消息来源:业务办    阅读次数:[]

报告题目: Energy landscape and rare events for biological jump processes 报告人:李铁军 教授,北京大学 报告时间:2017年5月23日下午15:30-17:30 报告地点:数学楼145学术报告厅 报告摘要: The construction of energy landscape for bio-dynamics is attracting more and more attention recent years. In this talk, I will introduce the strategy to construct the landscape from its connection with rare events, which relies on the large deviation theory for Gillespie-type jump dynamics. In the application to a typical genetic switching model, the two-scale large deviation theory is developed to take into account the fast switching of DNA states. The comparison with other proposals are also discussed. We demonstrate different diffusive limits arise when considering different regimes for genetic translation and switching processes. I will also talk about its applications in understanding the S-phase checkpoint activation mechanism for budding yeast. This is a joint work with Fangting Li, Xiaoguang Li, Cheng Lv and Peijie Zhou. 报告人简介:李铁军,国家优秀青年基金获得者,现为北京大学数学科学学院教授,博士生导师。主要从事复杂流体、化学反应随机动力学及随机微分方程数值解方面的研究。在复杂流体多尺度随机模型的数学分析、复杂网络的模型约化、化学反应随机动力学模拟方面有出色的工作,研究结果发表在《Proceedings of the National Academy of Sciences》(PNAS)等国际著名期刊上。李教授先后主持国家自然科学基金委青年、面上、优青及重点项目等多项重要科研项目,参加科技部973项目1项。现担任国际知名SCI期刊《Communications in Mathematical Sciences》及“计算数学”的编委。



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